When children at young age are exposed to cancer treatment methods such as radiation and chemotherapy, their tissues of heart and brain are damaged as they are not prone to these treatments. Their tissues, which are still in development stage in this age, are not immune to programmed cell death or apoptosis.
Apoptosis is a procedure where molecular signals, generated from the machines, command the cells to destruct themselves. Hence, apoptosis plays a crucial role in the development of a cell.
These treatments, which turn out to be toxic stressors, are a high risk to children and can cause never-ending damage in their heart and brain.
On the other hand, having conducted apoptosis on the brain at an early age also triggers an action that will generate high sensitivity to any type of pressure or stress which involves chemotherapy or radiation. This was claimed by Kristopher A. Sarosiek. Kristopher is the leading author and works at the Harvard T.H. Chan School of Public Health as an Assistant Professor.
He further claimed that not all the cancer cells die in the treatment. Some of them escape and activate the ‘pro-survival’ signals. A test was conducted which can measure the amount of ‘pro-survival’ signals in the cells. This test was called as BH3 and was conducted by Anthony Letai who works in Massachusetts at Dana-Farber Cancer Institute.
A cell with high cancer tissue is killed in the treatment, while a cell with a low rate of cancer tissue is saved.
Well, even though the treatment has a mixed blessing, it is likely to cause more damage to the young-aged and this should be stopped immediately with an alternate solution.